Fau Gene Summary [Mouse]
A structural constituent of ribosome. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide and defense response to Gram-positive bacterium. Part of cytosolic small ribosomal subunit. Is expressed in decidua; embryo; and uterus. Orthologous to human FAU (FAU ubiquitin like and ribosomal protein S30 fusion). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fau |
| Official Name | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived) [Source:MGI Symbol;Acc:MGI:102547] |
| Ensembl ID | ENSMUSG00000038274 |
| Bio databases IDs | |
| Aliases | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived) |
| Synonyms | asr1, eS30, FAU1, FAU ubiquitin like and ribosomal protein S30 fusion, Finkel-biskis-reilly murine sarcoma virus ubiquitously expressed, Fub1, Fubi, MNSFB, MNSFbeta, Mnsf β, RPS30, S30 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fau often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ubiquitin family
- structural constituent of ribosome
- Ubl1_cv_Nsp3_N-like
- Ubiquitin homologues
- protein binding
- Ribosomal protein S30
- ubiquitin-like domain
- RNA binding
Pathways
Biological processes and signaling networks where the Fau gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- rheumatoid arthritis
- survival
- infection by vesicular stomatitis virus
role in cell
- cell death
- replication in
- apoptosis
- nuclear export in
- processing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- ribosome
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fau gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- innate immune response in mucosa
- cytoplasmic translation
- antibacterial humoral response
- defense response to Gram-positive bacterium
- translation
Cellular Component
Where in the cell the gene product is active
- extracellular space
- cytosolic ribosome
- cytosolic small ribosomal subunit
- cytoplasm
- cytosol
- small ribosomal subunit
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome