Galnt18 Gene Summary [Mouse]
Predicted to enable polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including alimentary system; central nervous system; cranium; respiratory system; and sensory organ. Orthologous to human GALNT18 (polypeptide N-acetylgalactosaminyltransferase 18). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Galnt18 |
| Official Name | polypeptide N-acetylgalactosaminyltransferase 18 [Source:MGI Symbol;Acc:MGI:2446239] |
| Ensembl ID | ENSMUSG00000038296 |
| Bio databases IDs | |
| Aliases | polypeptide N-acetylgalactosaminyltransferase 18 |
| Synonyms | 2900011G21RIK, GalNAc-T15, GALNACT18, GALNT15, Galnt8, GALNTL4, LOC105376551, mpp-GalNAc-T18(O18), polypeptide N-acetylgalactosaminyltransferase 18, RGD1309623 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Galnt18 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ricin-type beta-trefoil lectin domain
- Glycosyl transferase family 2
- Ricin-type beta-trefoil
- polypeptide N-acetylgalactosaminyltransferase
- N-terminal domain of galactosyltransferase
- enzyme
- ricin B-type lectin domain, beta-trefoil fold
- glycosyltransferase family A
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- ischemic stroke
- non-insulin-dependent diabetes mellitus
- preeclampsia
- cardiomyopathy
- gallstone
- asthma
- COVID-19
- stroke
- major depression
- alcoholism
regulates
- cisplatin
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Galnt18 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein O-linked glycosylation
Cellular Component
Where in the cell the gene product is active
- Golgi apparatus
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- metal ion binding
- carbohydrate binding
- polypeptide N-acetylgalactosaminyltransferase activity