C1rl Gene Summary [Mouse]
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in zymogen activation. Located in extracellular space. Is expressed in cartilage; stomach; and testis. Orthologous to human C1RL (complement C1r subcomponent like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | C1rl |
| Official Name | complement component 1, r subcomponent-like [Source:MGI Symbol;Acc:MGI:2660692] |
| Ensembl ID | ENSMUSG00000038527 |
| Bio databases IDs | |
| Aliases | complement component 1, r subcomponent-like |
| Synonyms | C1RL1, C1RLP, CLSPa, complement C1r subcomponent like, complement component 1, r subcomponent-like |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse C1rl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- CUB
- peptidase
- active site
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse C1rl gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- zymogen activation
- innate immune response
- complement activation, classical pathway
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular vesicular exosome
Molecular Function
What the gene product does at the molecular level
- serine-type endopeptidase activity