Mrps34 Gene Summary [Mouse]

Predicted to be a structural constituent of ribosome. Involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; genitourinary system; heart; liver; and thymus primordium. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 32. Orthologous to human MRPS34 (mitochondrial ribosomal protein S34). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mrps34
Official Name
mitochondrial ribosomal protein S34 [Source:MGI Symbol;Acc:MGI:1930188]
Ensembl ID
ENSMUSG00000038880
Bio databases IDs NCBI: 79044 Ensembl: ENSMUSG00000038880
Aliases mitochondrial ribosomal protein S34
Synonyms 0610007F04Rik, 5330430D13Rik, COXPD32, mitochondrial ribosomal protein S34, MRP-S12, mS34, S34mt, Tce2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrps34 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • structural constituent of ribosome
  • Mitochondrial 28S ribosomal protein S34

Pathways

Biological processes and signaling networks where the Mrps34 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hereditary disorder
  • Leigh syndrome
  • combined oxidative phosphorylation deficiency 32
regulated by
  • beta-estradiol

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus
  • Mitochondria
  • mitochondrial matrix
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrps34 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.