Strip2 Gene Summary [Mouse]
Predicted to be involved in cell migration; cytoskeleton organization; and regulation of cell shape. Predicted to be located in cytoplasm. Predicted to be part of FAR/SIN/STRIPAK complex. Predicted to be active in cytosol. Is expressed in brain and cochlea epithelium. Orthologous to human STRIP2 (striatin interacting protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Strip2 |
| Official Name | striatin interacting protein 2 [Source:MGI Symbol;Acc:MGI:2444363] |
| Ensembl ID | ENSMUSG00000039629 |
| Bio databases IDs | |
| Aliases | striatin interacting protein 2 |
| Synonyms | D330017J20Rik, FAM40B, FAR11B, Myoscape, striatin interacting protein 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Strip2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain of unknown function (DUF3402)
- N1221-like protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- organismal death
- Huntington disease
- non-small cell lung cancer
- metastasis
regulated by
- 4-[4-[[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid
- SCN9A
- PBMCs
role in cell
- invasion
- expression in
- proliferation
- migration
- organization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Strip2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of cell shape
- cytoskeleton organization
- cell migration
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol