Strn4 Gene Summary [Mouse]
Predicted to enable several functions, including armadillo repeat domain binding activity; calmodulin binding activity; and protein phosphatase 2A binding activity. Predicted to be involved in negative regulation of hippo signaling. Predicted to be located in dendritic spine. Predicted to be part of FAR/SIN/STRIPAK complex. Predicted to be active in dendrite. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and musculoskeletal system. Orthologous to human STRN4 (striatin 4). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Strn4 |
| Official Name | striatin, calmodulin binding protein 4 [Source:MGI Symbol;Acc:MGI:2142346] |
| Ensembl ID | ENSMUSG00000030374 |
| Bio databases IDs | |
| Aliases | striatin, calmodulin binding protein 4 |
| Synonyms | PPP2R6C, STR4, striatin 4, striatin, calmodulin binding protein 4, ZIN, zinedin |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Strn4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- WD40 repeats
- protein phosphatase binding
- protein binding activity, bridging
- WD domain, G-beta repeat
- WD40
- protein domain specific binding
- protein binding
- Striatin family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- glutaminergic synapse
- postsynaptic region
- cellular membrane
- Plasma Membrane
- cytosol
- dendritic spines
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Strn4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of hippo signaling cascade
Cellular Component
Where in the cell the gene product is active
- dendrite
- cytoplasm
- dendritic spine
Molecular Function
What the gene product does at the molecular level
- calmodulin binding
- protein binding
- armadillo repeat domain binding
- protein binding, bridging
- protein phosphatase 2A binding