Rhbdd2 Gene Summary [Mouse]
Predicted to enable serine-type endopeptidase activity. Located in Golgi membrane and perinuclear region of cytoplasm. Is expressed in several structures, including eye; gonad; hemolymphoid system gland; liver; and lung. Orthologous to human RHBDD2 (rhomboid domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rhbdd2 |
| Official Name | rhomboid domain containing 2 [Source:MGI Symbol;Acc:MGI:1915612] |
| Ensembl ID | ENSMUSG00000039917 |
| Bio databases IDs | |
| Aliases | rhomboid domain containing 2 |
| Synonyms | 0610011L13RIK, NPD007, RHBDL7, rhomboid domain containing 2, Usmg1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rhbdd2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Rhomboid family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- perinuclear region
- Golgi Apparatus
- Mitochondria
- Golgi membrane
- nucleoplasm
- photoreceptor inner segments
- perikaryon
- cone inner segments
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rhbdd2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- endoplasmic reticulum unfolded protein response
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- perinuclear region of cytoplasm
- Golgi membrane
- Golgi apparatus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- serine-type endopeptidase activity
- signal recognition particle binding