Lrrc52 Gene Summary [Mouse]

Enables potassium channel activity. Acts upstream of or within establishment of localization in cell and potassium ion transport. Predicted to be located in plasma membrane. Predicted to be part of voltage-gated potassium channel complex. Orthologous to human LRRC52 (leucine rich repeat containing 52). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Lrrc52
Official Name
leucine rich repeat containing 52 [Source:MGI Symbol;Acc:MGI:1924118]
Ensembl ID
ENSMUSG00000040485
Bio databases IDs NCBI: 240899 Ensembl: ENSMUSG00000040485
Aliases leucine rich repeat containing 52
Synonyms 4930413P14Rik, leucine rich repeat containing 52, RGD1312014
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lrrc52 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • potassium channel
  • channel regulator
  • voltage-gated potassium channel
  • potassium channel regulator
  • Leucine rich repeat
  • ion channel binding
  • protein binding
  • Leucine rich repeat N-terminal domain
  • Leucine Rich repeats (2 copies)
  • ion channel

Pathways

Biological processes and signaling networks where the Lrrc52 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Lrrc52 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • potassium ion transmembrane transport
  • reproductive process
  • establishment of localization in cell

Cellular Component

Where in the cell the gene product is active
  • voltage-gated potassium channel complex
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • voltage-gated potassium channel activity
  • protein binding
  • ion channel binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.