Nrn1

Enables identical protein binding activity. Involved in presynaptic modulation of chemical synaptic transmission and regulation of synapse maturation. Acts upstream of or within neuron projection extension. Located in extracellular space and plasma membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and liver. Orthologous to human NRN1 (neuritin 1). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nrn1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Nrn1 gene, providing context for its role in the cell.