Arhgef10l

Predicted to enable GTPase activator activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in SREBP signaling pathway; actin cytoskeleton organization; and positive regulation of stress fiber assembly. Predicted to be active in cytosol. Is expressed in brain; facial prominence ectoderm; facial prominence mesenchyme; liver; and testis. Human ortholog(s) of this gene implicated in ovarian endometrial cancer and ovarian serous carcinoma. Orthologous to human ARHGEF10L (Rho guanine nucleotide exchange factor 10 like). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Arhgef10l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Arhgef10l gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Arhgef10l gene, providing context for its role in the cell.