Ostc Gene Summary [Mouse]

Predicted to be involved in protein glycosylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of oligosaccharyltransferase complex. Is expressed in several structures, including Meckel's cartilage; central nervous system; pancreas epithelium; retina; and skeleton. Orthologous to human OSTC (oligosaccharyltransferase complex non-catalytic subunit). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ostc
Official Name
oligosaccharyltransferase complex subunit (non-catalytic) [Source:MGI Symbol;Acc:MGI:1913607]
Ensembl ID
ENSMUSG00000041084
Bio databases IDs NCBI: 66357 Ensembl: ENSMUSG00000041084
Aliases oligosaccharyltransferase complex subunit (non-catalytic)
Synonyms 2310008M10Rik, 5730557H03Rik, DC2, oligosaccharyltransferase complex non-catalytic subunit, oligosaccharyltransferase complex subunit (non-catalytic), RGD1560708
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ostc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding activity, bridging
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • aldosterone producing adrenocortical adenoma
  • adenoma formation
  • cutaneous sarcoidosis
regulated by
regulates
  • asparagine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ostc gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein N-linked glycosylation
  • protein N-linked glycosylation via asparagine

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • oligosaccharyltransferase complex

Molecular Function

What the gene product does at the molecular level
  • dolichyl-diphosphooligosaccharide-protein glycotransferase activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

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