B4galnt3 Gene Summary [Mouse]

Predicted to enable acetylgalactosaminyltransferase activity. Predicted to be involved in chondroitin sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi apparatus. Orthologous to human B4GALNT3 (beta-1,4-N-acetyl-galactosaminyltransferase 3). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Processed Transcript
Official Symbol
B4galnt3
Official Name
beta-1,4-N-acetyl-galactosaminyl transferase 3 [Source:MGI Symbol;Acc:MGI:3041155]
Ensembl ID
ENSMUSG00000041372
Bio databases IDs NCBI: 330406 Ensembl: ENSMUSG00000041372
Aliases beta-1,4-N-acetyl-galactosaminyl transferase 3
Synonyms B4GalNAcT3, beta-1,4-N-acetyl-galactosaminyl transferase 3, beta 1,4-N-ACETYLGALACTOSYLAMINYL TRANSFERASE 3, C330047A21, RGD1561056, β-1,4-N-acetyl-galactosaminyl transferase 3, β 1,4-N-ACETYLGALACTOSYLAMINYL TRANSFERASE 3
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse B4galnt3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • acetylgalactosaminyltransferase
  • PA14 domain
  • N-terminal domain of galactosyltransferase
  • enzyme
  • glycosyltransferase family A

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • COVID-19
  • idiopathic scoliosis
  • obesity
  • fracture of bone
  • severe COVID-19
  • polyneuropathy
regulated by
  • doxorubicin
  • cisplatin
  • ifosfamide
  • methotrexate
  • IL10RA
regulates
  • N,N'-diacetylgalactosediamine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • intracellular membrane-bounded organelle
  • Golgi Apparatus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse B4galnt3 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • intracellular membrane-bounded organelle
  • Golgi cisterna membrane
  • Golgi apparatus

Molecular Function

What the gene product does at the molecular level
  • acetylgalactosaminyltransferase activity
  • N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.