Uggt2 Gene Summary [Mouse]

Predicted to enable UDP-glucose:glycoprotein glucosyltransferase activity and unfolded protein binding activity. Predicted to be involved in protein N-linked glycosylation via asparagine. Predicted to be part of protein-containing complex. Predicted to be active in endoplasmic reticulum. Orthologous to human UGGT2 (UDP-glucose glycoprotein glucosyltransferase 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Retained Intron
Official Symbol
Uggt2
Official Name
UDP-glucose glycoprotein glucosyltransferase 2 [Source:MGI Symbol;Acc:MGI:1913685]
Ensembl ID
ENSMUSG00000042104
Bio databases IDs NCBI: 66435 Ensembl: ENSMUSG00000042104
Aliases UDP-glucose glycoprotein glucosyltransferase 2
Synonyms 1810064L21RIK, 3110001A05Rik, 3110027P15RIK, A230065J02RIK, AW047562, HUGT2, RGD1562426, RGD1563520, UDP-glucose glycoprotein glucosyltransferase 2, UGCGL2, UGGG2, UGT2
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Uggt2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • thioredoxin-like domain
  • catalytic domain
  • Glucosyltransferase 24
  • UDP-glucose:glycoprotein glucosyltransferase
  • enzyme
  • protein binding
  • glycosyltransferase family A

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetes mellitus
  • vascular disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Endoplasmic Reticulum
  • endoplasmic reticulum lumen

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Uggt2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein N-linked glycosylation via asparagine

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum lumen
  • macromolecular complex
  • endoplasmic reticulum
  • endoplasmic reticulum-Golgi intermediate compartment

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • unfolded protein binding
  • UDP-glucose:glycoprotein glucosyltransferase activity

Gene-Specific Assays for Results You Can Trust

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