Ppig Gene Summary [Mouse]
Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding and protein peptidyl-prolyl isomerization. Predicted to be located in cytosol; nuclear matrix; and nuclear speck. Predicted to be active in cytoplasm and nucleus. Orthologous to human PPIG (peptidylprolyl isomerase G). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Ppig |
| Official Name | peptidyl-prolyl isomerase G (cyclophilin G) [Source:MGI Symbol;Acc:MGI:2445173] |
| Ensembl ID | ENSMUSG00000042133 |
| Bio databases IDs | |
| Aliases | peptidyl-prolyl isomerase G (cyclophilin G) |
| Synonyms | AU019516, B230312B02RIK, CARS-Cyp, CLK ASSOCIATED RS CYCLOPHILIN, CYP, D5Mgi12, peptidylprolyl isomerase G, peptidyl-prolyl isomerase G (cyclophilin G), SCAF10, SRCyp |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppig often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- peptidylprolyl isomerase
- Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
- cyclophilin
- cyclosporin A binding
- Moca domain
- enzyme
- protein binding
- cyclin-binding domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- cytosol
- nuclear foci
- nucleoplasm
- interchromatin granule clusters
- nuclear speckles
- nuclear matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ppig gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- protein peptidyl-prolyl isomerization
- protein folding
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- nuclear speck
- mitochondrion
- cytosol
- nuclear matrix
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- cyclosporin A binding
- peptidyl-prolyl cis-trans isomerase activity
- RNA binding
- protein binding