Luc7l Gene Summary [Mouse]
Enables RS domain binding activity. Acts upstream of or within negative regulation of striated muscle tissue development. Predicted to be part of U1 snRNP and U2-type prespliceosome. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human LUC7L (LUC7 like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Luc7l |
| Official Name | Luc7-like [Source:MGI Symbol;Acc:MGI:1914228] |
| Ensembl ID | ENSMUSG00000024188 |
| Bio databases IDs | |
| Aliases | Luc7-like |
| Synonyms | 1810045C04Rik, 2410018D03Rik, hLuc7B1, LOC100360956, Luc7, LUC7B1, Luc7l1, LUC7-like, Polybinding protein, cytoplasmic 1, SR+89 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Luc7l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RS domain binding
- LUC7 N_terminus
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Luc7l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mRNA splice site selection
- negative regulation of striated muscle tissue development
Cellular Component
Where in the cell the gene product is active
- U2-type prespliceosome
- U1 snRNP
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- mRNA binding
- RS domain binding