Sprr2d Gene Summary [Mouse]
Predicted to enable lipid binding activity. Predicted to be a structural constituent of skin epidermis. Involved in female gonad development. Acts upstream of or within response to estradiol. Located in cytoplasm and nucleus. Is expressed in reproductive system and skin. Orthologous to several human genes including SPRR2A (small proline rich protein 2A); SPRR2B (small proline rich protein 2B); and SPRR2D (small proline rich protein 2D). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sprr2d |
| Official Name | small proline-rich protein 2D [Source:MGI Symbol;Acc:MGI:1330347] |
| Ensembl ID | ENSMUSG00000042212 |
| Bio databases IDs | |
| Aliases | small proline-rich protein 2D |
| Synonyms | small proline-rich protein 2D |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sprr2d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- lipid binding
- structural constituent of epidermis
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cornified envelope
- Extracellular Space
- Nucleus
- secretory granules