Mideas Gene Summary [Mouse]
Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of histone deacetylase complex and transcription regulator complex. Is expressed in brain; cerebral cortex; and telencephalon ventricular layer. Orthologous to human MIDEAS (mitotic deacetylase associated SANT domain protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mideas |
| Official Name | mitotic deacetylase associated SANT domain protein [Source:MGI Symbol;Acc:MGI:2685106] |
| Ensembl ID | ENSMUSG00000042507 |
| Bio databases IDs | |
| Aliases | mitotic deacetylase associated SANT domain protein |
| Synonyms | 9430029N19RIK, C130039O16Rik, c14 5541, C14orf117, C14orf43, ELMSAN1, Gm260, LOC101928293, LSR68, mitotic deacetylase associated SANT domain protein, RGD1306119 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mideas often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SANT
- transcription regulator
- SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
- ELM2 domain
- Myb-like DNA-binding domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mideas gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription, DNA-dependent
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- transcription factor complex
- histone deacetylase complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- transcription corepressor activity