Hirip3 Gene Summary [Mouse]
Predicted to enable H2A-H2B histone complex chaperone activity. Predicted to be involved in chromatin organization. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in nucleus. Is expressed in central nervous system; genitourinary system; and intestine. Orthologous to human HIRIP3 (HIRA interacting protein 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hirip3 |
| Official Name | HIRA interacting protein 3 [Source:MGI Symbol;Acc:MGI:2142364] |
| Ensembl ID | ENSMUSG00000042606 |
| Bio databases IDs | |
| Aliases | HIRA interacting protein 3 |
| Synonyms | B130036003, B130036O03, C86302, HIRA interacting protein 3, Sodium/potassium/calcium exchanger 1 precursor |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Hirip3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Histone chaperone domain CHZ
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Hirip3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chromatin organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding