Spata46 Gene Summary [Mouse]
Involved in fusion of sperm to egg plasma membrane involved in single fertilization and spermatogenesis. Located in nuclear membrane. Orthologous to human SPATA46 (spermatogenesis associated 46). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Spata46 |
| Official Name | spermatogenesis associated 46 [Source:MGI Symbol;Acc:MGI:1924175] |
| Ensembl ID | ENSMUSG00000042800 |
| Bio databases IDs | |
| Aliases | spermatogenesis associated 46 |
| Synonyms | 1700015E13Rik, C1orf111, HSD20, RGD1565283, spermatogenesis associated 46, TEKT2BP2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Spata46 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Spermatogenesis-associated protein 46
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Spata46 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatogenesis
- cell differentiation
- fertilization
- fusion of sperm to egg plasma membrane
Cellular Component
Where in the cell the gene product is active
- nuclear membrane
Molecular Function
What the gene product does at the molecular level
- protein binding