Tmem186 Gene Summary [Mouse]
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Orthologous to human TMEM186 (transmembrane protein 186). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem186 |
| Official Name | transmembrane protein 186 [Source:MGI Symbol;Acc:MGI:1913940] |
| Ensembl ID | ENSMUSG00000043140 |
| Bio databases IDs | |
| Aliases | transmembrane protein 186 |
| Synonyms | 2810440M13Rik, 4432406C05Rik, C16orf51, transmembrane protein 186 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem186 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- TMEM70/TMEM186/TMEM223 protein family
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem186 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial respiratory chain complex I assembly
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding