Kcnrg Gene Summary [Mouse]
Predicted to enable identical protein binding activity. Predicted to be involved in negative regulation of delayed rectifier potassium channel activity. Predicted to be active in endoplasmic reticulum. Orthologous to human KCNRG (potassium channel regulator). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kcnrg |
| Official Name | potassium channel regulator [Source:MGI Symbol;Acc:MGI:2685591] |
| Ensembl ID | ENSMUSG00000046168 |
| Bio databases IDs | |
| Aliases | potassium channel regulator |
| Synonyms | Clld4, DLTET, E030012H22Rik, Gm745, potassium channel regulator |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kcnrg often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- protein binding
- identical protein binding
- ion channel
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- diffuse large B-cell lymphoma
- B-cell non-Hodgkin disease
- mature B-cell neoplasia
- T-cell non-Hodgkin lymphoma
- T-cell non-Hodgkin disease
- follicular B-cell or T-cell lymphoma
- non-Hodgkin disease
regulated by
role in cell
- apoptosis
- proliferation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Kcnrg gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein homooligomerization
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding