Ap5b1 Gene Summary [Mouse]

Predicted to be involved in endosomal transport. Predicted to be located in late endosome. Predicted to be part of AP-type membrane coat adaptor complex. Orthologous to human AP5B1 (adaptor related protein complex 5 subunit beta 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ap5b1
Official Name
adaptor-related protein complex 5, beta 1 subunit [Source:MGI Symbol;Acc:MGI:2685808]
Ensembl ID
ENSMUSG00000049562
Bio databases IDs NCBI: 381201 Ensembl: ENSMUSG00000049562
Aliases adaptor-related protein complex 5, beta 1 subunit
Synonyms adaptor-related protein complex 5, beta 1 subunit, adaptor related protein complex 5 subunit beta 1, adaptor related protein complex 5 subunit β 1, adaptor-related protein complex 5, β 1 subunit, AP-5, Beta5, DKFZp761E198, Gm962, PP1030, RGD1562657, β-5
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ap5b1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Pathways

Biological processes and signaling networks where the Ap5b1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • systemic lupus erythematosus
  • psoriasis
regulates
role in cell
  • transport
  • trafficking in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ap5b1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • vesicle-mediated transport
  • protein transport
  • endosomal transport

Cellular Component

Where in the cell the gene product is active
  • AP-type membrane coat adaptor complex
  • late endosome
  • AP-5 adaptor complex
  • lysosomal membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.