Rpl27a Gene Summary [Mouse]
A structural constituent of ribosome. Acts upstream of or within translation. Located in cytosolic ribosome. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in endolymphatic appendage and head. Orthologous to human RPL27A (ribosomal protein L27a). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpl27a |
| Official Name | ribosomal protein L27A [Source:MGI Symbol;Acc:MGI:1347076] |
| Ensembl ID | ENSMUSG00000046364 |
| Bio databases IDs | |
| Aliases | ribosomal protein L27A |
| Synonyms | L27', L27A, L29, MGC10850, ribosomal protein L27A, uL15 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpl27a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
- structural constituent of ribosome
- PRK04005
- protein binding
- RNA binding
Pathways
Biological processes and signaling networks where the Rpl27a gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- interchromatin granule cluster fractions
- pH resistant lipid raft fraction
- detergent resistant lipid raft fraction
- ribosome
- Endoplasmic Reticulum
- cytosol
- nucleoplasm
- nucleoli
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpl27a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- translation
Cellular Component
Where in the cell the gene product is active
- cytosolic ribosome
- cytoplasm
- membrane
- cytosol
- endoplasmic reticulum
- cytosolic large ribosomal subunit
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- structural constituent of ribosome