Rpl9 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to act upstream of or within translation. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Orthologous to human RPL9 (ribosomal protein L9). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Rpl9 |
| Official Name | ribosomal protein L9 [Source:MGI Symbol;Acc:MGI:1298373] |
| Ensembl ID | ENSMUSG00000047215 |
| Bio databases IDs | |
| Aliases | ribosomal protein L9 |
| Synonyms | L9, LOC100362838, NPC-A-16, Pkc substrate 80 k-h, ribosomal protein L9, uL6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpl9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribosomal protein uL6, archaeal form
- structural constituent of ribosome
- protein binding
- Ribosomal protein L6
- RNA binding
Pathways
Biological processes and signaling networks where the Rpl9 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metabolic syndrome X
- Diamond-Blackfan anemia
- leiomyoma
- leiomyomatosis
- peripheral arterial disease
- paroxysmal nocturnal hemoglobinuria
- cholangiocarcinoma
- cholangiocarcinoma cancer
regulates
role in cell
- cell death
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- ribosome
- Nucleus
- cytosol
- nucleoli
- nuclear envelope
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpl9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- translation
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosolic ribosome
- focal adhesion
- cytoplasm
- membrane
- cytosol
- cytosolic large ribosomal subunit
- ribosome
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome
- rRNA binding