Mex3d Gene Summary [Mouse]
Predicted to enable mRNA 3'-UTR AU-rich region binding activity. Predicted to be involved in mRNA destabilization. Predicted to act upstream of or within RNA destabilization and mRNA catabolic process. Predicted to be located in nucleus and perinuclear region of cytoplasm. Is expressed in cerebral cortex intermediate zone; cerebral cortex subventricular zone; and cortical plate. Orthologous to human MEX3D (mex-3 RNA binding family member D). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mex3d |
| Official Name | mex3 RNA binding family member D [Source:MGI Symbol;Acc:MGI:2681847] |
| Ensembl ID | ENSMUSG00000048696 |
| Bio databases IDs | |
| Aliases | mex3 RNA binding family member D |
| Synonyms | MEX3, mex-3 RNA binding family member D, OK/SW-cl.4, RKHD1, RNF193, TINO |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mex3d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- mRNA 3' UTR binding
- K homology (KH) RNA-binding domain, type I
- KH domain
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Ring finger
- K homology RNA-binding domain
- Ring finger domain
- Zinc finger, C3HC4 type (RING finger)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- perinuclear region
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mex3d gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mRNA destabilization
- posttranscriptional regulation of gene expression by mRNA localization
Cellular Component
Where in the cell the gene product is active
- nucleus
- perinuclear region of cytoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- mRNA 3'-UTR AU-rich region binding
- metal ion binding