MEX3D Gene Summary [Human]

Enables mRNA 3'-UTR AU-rich region binding activity. Located in nucleus and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
MEX3D
Official Name
mex-3 RNA binding family member D [Source:HGNC Symbol;Acc:HGNC:16734]
Ensembl ID
ENSG00000181588
Bio databases IDs NCBI: 399664 Ensembl: ENSG00000181588
Aliases mex-3 RNA binding family member D, bcl-2 ARE RNA binding protein
Synonyms MEX3, mex-3 RNA binding family member D, OK/SW-cl.4, RKHD1, RNF193, TINO
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MEX3D often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • mRNA 3' UTR binding
  • K homology (KH) RNA-binding domain, type I
  • KH domain
  • RING finger (Really Interesting New Gene) domain and U-box domain superfamily
  • Ring finger
  • K homology RNA-binding domain
  • Ring finger domain
  • Zinc finger, C3HC4 type (RING finger)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • uterine leiomyoma
  • leiomyomatosis
regulated by
  • NDRG3
  • dimethyl n-oxalyl-glycine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • perinuclear region

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human MEX3D gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mRNA destabilization
  • posttranscriptional regulation of gene expression by mRNA localization

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • perinuclear region of cytoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • mRNA 3'-UTR AU-rich region binding
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.