Frmd3 Gene Summary [Mouse]
Predicted to enable cytoskeletal protein binding activity. Predicted to be involved in actomyosin structure organization. Predicted to be located in membrane. Predicted to be active in cytoskeleton. Used to study triple-receptor negative breast cancer. Orthologous to human FRMD3 (FERM domain containing 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Frmd3 |
| Official Name | FERM domain containing 3 [Source:MGI Symbol;Acc:MGI:2442466] |
| Ensembl ID | ENSMUSG00000049122 |
| Bio databases IDs | |
| Aliases | FERM domain containing 3 |
| Synonyms | 4.1O, 9430066I12RIK, EPB41L4O, EPB41LO, FERM domain containing 3, LOC105376113, P410 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Frmd3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FERM adjacent (FA)
- FERM central domain
- Band 4.1 homologues
- Ubl1_cv_Nsp3_N-like
- protein binding
- Pleckstrin homology-like domain
- FERM domain B-lobe
- FERM C-terminal PH-like domain
- FERM N-terminal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Frmd3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- actomyosin structure organization
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- cytoskeletal protein binding