Cmtm7 Gene Summary [Mouse]
Predicted to enable cytokine activity. Acts upstream of or within B-1a B cell differentiation. Predicted to be located in extracellular space. Predicted to be active in membrane. Is expressed in thymus primordium. Orthologous to human CMTM7 (CKLF like MARVEL transmembrane domain containing 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cmtm7 |
| Official Name | CKLF-like MARVEL transmembrane domain containing 7 [Source:MGI Symbol;Acc:MGI:2447166] |
| Ensembl ID | ENSMUSG00000032436 |
| Bio databases IDs | |
| Aliases | CKLF-like MARVEL transmembrane domain containing 7 |
| Synonyms | CKLF-like MARVEL transmembrane domain containing 7, CKLFSF7, LNV |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cmtm7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Membrane-associating domain
- protein binding
- cytokine
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- organismal death
- hallux valgus
- idiopathic scoliosis
- venous thromboembolism
- vascular dementia
- herpes zoster
role in cell
- proliferation
- expression in
- phosphorylation in
- production in
- dexamethasone sensitivity
- differentiation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cmtm7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chemotaxis
- B-1a B cell differentiation
- signal transduction
Cellular Component
Where in the cell the gene product is active
- extracellular space
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- cytokine activity