Purg Gene Summary [Mouse]
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and purine-rich negative regulatory element binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is active in synapse. Is expressed in glossopharyngeal ganglion and midbrain mantle layer. Orthologous to human PURG (purine rich element binding protein G). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Purg |
| Official Name | purine-rich element binding protein G [Source:MGI Symbol;Acc:MGI:1922279] |
| Ensembl ID | ENSMUSG00000049184 |
| Bio databases IDs | |
| Aliases | purine-rich element binding protein G |
| Synonyms | 4930486B15Rik, PURG-A, PURG-B, purine-rich element binding protein G |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Purg often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PUR domain
- Protein of unknown function (DUF3276)
- PurA ssDNA and RNA-binding protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Purg gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- synapse
Molecular Function
What the gene product does at the molecular level
- RNA binding
- RNA polymerase II regulatory region sequence-specific DNA binding
- purine-rich negative regulatory element binding
- sequence-specific DNA binding RNA polymerase II transcription factor activity