Ccnq Gene Summary [Mouse]
Enables protein kinase activator activity. Acts upstream of or within positive regulation of MAPK cascade. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in nucleus. Is expressed in several structures, including adrenal gland; central nervous system; heart; pancreas; and retina. Human ortholog(s) of this gene implicated in syndactyly-telecanthus-anogenital and renal malformations syndrome. Orthologous to human CCNQ (cyclin Q). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ccnq |
| Official Name | cyclin Q [Source:MGI Symbol;Acc:MGI:1916359] |
| Ensembl ID | ENSMUSG00000049489 |
| Bio databases IDs | |
| Aliases | cyclin Q |
| Synonyms | 1810009O10Rik, cyclin Q, CycM, FAM58A, Fam58b, RGD1305651 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ccnq often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein kinase activator
- Cyclin box fold superfamily
- protein binding
- domain present in cyclins, TFIIB and Retinoblastoma
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ccnq gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- cyclin-dependent protein kinase holoenzyme complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- cyclin-dependent protein kinase regulator activity