AP5B1 Gene Summary [Human]
Involved in endosomal transport. Located in lysosomal membrane. Part of AP-type membrane coat adaptor complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | AP5B1 |
| Official Name | adaptor related protein complex 5 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:25104] |
| Ensembl ID | ENSG00000254470 |
| Bio databases IDs | |
| Aliases | adaptor related protein complex 5 subunit beta 1 |
| Synonyms | adaptor-related protein complex 5, beta 1 subunit, adaptor related protein complex 5 subunit beta 1, adaptor related protein complex 5 subunit β 1, adaptor-related protein complex 5, β 1 subunit, AP-5, Beta5, DKFZp761E198, Gm962, PP1030, RGD1562657, β-5 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human AP5B1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Pathways
Biological processes and signaling networks where the AP5B1 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human AP5B1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- vesicle-mediated transport
- protein transport
- endosomal transport
Cellular Component
Where in the cell the gene product is active
- AP-type membrane coat adaptor complex
- late endosome
- AP-5 adaptor complex
- lysosomal membrane
Molecular Function
What the gene product does at the molecular level
- protein binding