Pusl1 Gene Summary [Mouse]
Predicted to enable pseudouridine synthase activity. Predicted to be involved in tRNA pseudouridine synthesis. Predicted to be located in mitochondrion. Orthologous to human PUSL1 (pseudouridine synthase like 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Pusl1 |
| Official Name | pseudouridylate synthase-like 1 [Source:MGI Symbol;Acc:MGI:3047787] |
| Ensembl ID | ENSMUSG00000051557 |
| Bio databases IDs | |
| Aliases | pseudouridylate synthase-like 1 |
| Synonyms | 2810021I11Rik, FLJ90811, pseudouridine synthase like 1, pseudouridylate synthase-like 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pusl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tRNA pseudouridine(38-40) synthase
- PseudoU_synth
- tRNA pseudouridine synthase
- enzyme
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pusl1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- tRNA pseudouridine synthesis
Cellular Component
Where in the cell the gene product is active
- intracellular membrane-bounded organelle
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- RNA binding
- pseudouridine synthase activity