Rinl Gene Summary [Mouse]
Enables guanyl-nucleotide exchange factor activity. Acts upstream of or within endocytosis. Located in actin cytoskeleton and ruffle. Orthologous to human RINL (Ras and Rab interactor like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rinl |
| Official Name | Ras and Rab interactor-like [Source:MGI Symbol;Acc:MGI:2444024] |
| Ensembl ID | ENSMUSG00000051735 |
| Bio databases IDs | |
| Aliases | Ras and Rab interactor-like |
| Synonyms | 5830482F20RIK, 9930116N10Rik, Ras and Rab interactor-like, RGD1310133 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rinl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- VPS9p domain
- guanyl-nucleotide exchange factor
- Vacuolar sorting protein 9 (VPS9) domain
- Src homology 2 (SH2) domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- ruffle
- actin cytoskeleton
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rinl gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein transport
- endocytosis
Cellular Component
Where in the cell the gene product is active
- endocytic vesicle
- ruffle
- actin cytoskeleton
- cytosol
Molecular Function
What the gene product does at the molecular level
- guanyl-nucleotide exchange factor activity
- GTPase activator activity
- small GTPase binding