Surf6 Gene Summary [Mouse]
Enables DNA binding activity and RNA binding activity. Acts upstream of or within ribosome biogenesis. Located in granular component and nucleoplasm. Is expressed in several structures, including early conceptus and oocyte. Orthologous to human SURF6 (surfeit 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Surf6 |
| Official Name | surfeit gene 6 [Source:MGI Symbol;Acc:MGI:98447] |
| Ensembl ID | ENSMUSG00000036160 |
| Bio databases IDs | |
| Aliases | surfeit gene 6 |
| Synonyms | D2Wsu129e, RRP14, surfeit 6, surfeit gene 6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Surf6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Surfeit locus protein 6
- protein binding activity, bridging
- protein binding
- DNA binding
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- granular components
- chromosome
- nucleoplasm
- nucleoli
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Surf6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosomal large subunit biogenesis
- ribosomal small subunit biogenesis
Cellular Component
Where in the cell the gene product is active
- granular component
- chromosome
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- RNA binding
- protein binding