Gas5 Gene Summary [Mouse]
Acts upstream of or within several processes, including bone development; mRNA catabolic process; and osteoblast differentiation. Is expressed in several structures, including alimentary system; brain; metanephros; respiratory system; and sensory organ. Orthologous to human GAS5 (growth arrest specific 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Gas5 |
| Official Name | growth arrest specific 5 [Source:MGI Symbol;Acc:MGI:95659] |
| Ensembl ID | ENSMUSG00000053332 |
| Bio databases IDs | |
| Aliases | growth arrest specific 5 |
| Synonyms | growth arrest specific 5, LOC348531, Mir5117, NCRNA00030, SNHG2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gas5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hepatocellular carcinoma
- liver cancer
- epithelial cancer
- organismal death
- hypertension
- capillary leak syndrome
- ovarian cancer
- asthma
- non-small cell lung cancer
- Klinefelter syndrome
role in cell
- expression in
- proliferation
- invasion by
- cell viability
- apoptosis
- cell death
- quantity
- migration
- phosphorylation in
- activation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown