Try4 Gene Summary [Mouse]
Enables serine-type endopeptidase activity. Predicted to be involved in proteolysis. Located in collagen-containing extracellular matrix. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and respiratory system. Human ortholog(s) of this gene implicated in pancreatitis. Orthologous to several human genes including PRSS1 (serine protease 1) and PRSS2 (serine protease 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Try4 |
| Official Name | trypsin 4 [Source:MGI Symbol;Acc:MGI:102757] |
| Ensembl ID | ENSMUSG00000054106 |
| Bio databases IDs | |
| Aliases | trypsin 4 |
| Synonyms | 0910001B19Rik, 1810049H19Rik, Prss3, serine protease 3, T8, T9, Tc, Td, Tesp4, Trpd, Try4, Try5, trypsin 4, trypsin 5, Trypsinogen 8 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Try4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- serine endopeptidase
- serine-type peptidase
- peptidase
- calcium ion binding
Pathways
Biological processes and signaling networks where the Try4 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- acrosome