Ctrb1 Gene Summary [Mouse]
Enables serine-type endopeptidase activity. Acts upstream of or within proteolysis. Predicted to be located in extracellular region. Is expressed in ovary; pancreas; pancreas tip epithelium; and testis. Orthologous to several human genes including CTRB1 (chymotrypsinogen B1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ctrb1 |
| Official Name | chymotrypsinogen B1 [Source:MGI Symbol;Acc:MGI:88559] |
| Ensembl ID | ENSMUSG00000031957 |
| Bio databases IDs | |
| Aliases | chymotrypsinogen B1 |
| Synonyms | 2200008D09Rik, Chymotrypsin, Chymotrypsinogen B, chymotrypsinogen B1, Ctrb, LOC687247, Prt-2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ctrb1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- serine endopeptidase
- serine-type peptidase
- peptidase
- protein binding
- chymotrypsin
Pathways
Biological processes and signaling networks where the Ctrb1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- Endoplasmic Reticulum
- ER-to-Golgi intermediate compartment
- endoplasmic reticulum buds