Emcn Gene Summary [Mouse]
Predicted to enable carbohydrate binding activity. Acts upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in plasma membrane. Is expressed in several structures, including cardiovascular system; early conceptus; hemolymphoid system; lung; and urinary system. Orthologous to human EMCN (endomucin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Emcn |
| Official Name | endomucin [Source:MGI Symbol;Acc:MGI:1891716] |
| Ensembl ID | ENSMUSG00000054690 |
| Bio databases IDs | |
| Aliases | endomucin |
| Synonyms | 0610012K22Rik, EMCN2, endomucin, MUC14 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Emcn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Endomucin
- protein binding
- carbohydrate binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- ischemic stroke
- non-small cell lung cancer
- primary central nervous system lymphoma
- primary cancer
- lymphomagenesis
- central nervous system cancer
- COVID-19
- open-angle glaucoma
- insomnia
- uterine leiomyoma
role in cell
- adhesion
- homeostasis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Emcn gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular region
- plasma membrane