Emcn Gene Summary [Rat]
Predicted to enable carbohydrate binding activity. Predicted to be involved in angiogenesis; cell-cell adhesion; and regulation of cell adhesion. Predicted to act upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in plasma membrane. Orthologous to human EMCN (endomucin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Emcn |
| Official Name | endomucin [Source:RGD Symbol;Acc:1303218] |
| Ensembl ID | ENSRNOG00000022910 |
| Bio databases IDs | |
| Aliases | endomucin |
| Synonyms | 0610012K22Rik, EMCN2, endomucin, MUC14 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Emcn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Endomucin
- protein binding
- carbohydrate binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- ischemic stroke
- non-small cell lung cancer
- primary central nervous system lymphoma
- primary cancer
- lymphomagenesis
- central nervous system cancer
- COVID-19
- open-angle glaucoma
- insomnia
- uterine leiomyoma
role in cell
- adhesion
- homeostasis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Emcn gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular region
- plasma membrane