Gemin6 Gene Summary [Mouse]
Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Predicted to be located in Gemini of Cajal bodies and cytosol. Predicted to be part of SMN complex. Is expressed in brain and spinal cord. Orthologous to human GEMIN6 (gem nuclear organelle associated protein 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Gemin6 |
| Official Name | gem nuclear organelle associated protein 6 [Source:MGI Symbol;Acc:MGI:1914492] |
| Ensembl ID | ENSMUSG00000055760 |
| Bio databases IDs | |
| Aliases | gem nuclear organelle associated protein 6 |
| Synonyms | 2610019B15Rik, 2810470M17Rik, gem (nuclear organelle) associated protein 6, gem nuclear organelle associated protein 6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gemin6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sm and related proteins
- Gemin6 Sm-like domain
- Gemin6 C-terminal domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
- gems
- nucleoplasm
- nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gemin6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spliceosomal complex assembly
- nuclear mRNA splicing, via spliceosome
- spliceosomal snRNP assembly
Cellular Component
Where in the cell the gene product is active
- nuclear body
- cytoplasm
- SMN-Sm protein complex
- cytosol
- SMN complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding