Lman1l Gene Summary [Mouse]

Predicted to enable D-mannose binding activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi membrane; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in metanephros and submandibular gland. Orthologous to human LMAN1L (lectin, mannose binding 1 like). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Lman1l
Official Name
lectin, mannose-binding 1 like [Source:MGI Symbol;Acc:MGI:2667537]
Ensembl ID
ENSMUSG00000056271
Bio databases IDs NCBI: 235416 Ensembl: ENSMUSG00000056271
Aliases lectin, mannose-binding 1 like
Synonyms COMPLEXIN 3, ERGIC-53L, ERGL, FLJ13993, lectin, mannose-binding 1 like, lectin, mannose-binding, 1 like, slamp
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lman1l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • legume lectins

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • exocytosis by
  • calcium triggered exocytosis in
  • priming in
  • miniature excitatory postsynaptic currents in
  • priming
  • exocytosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Lman1l gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ER to Golgi vesicle-mediated transport

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • ER to Golgi transport vesicle
  • Golgi membrane
  • endoplasmic reticulum-Golgi intermediate compartment
  • endoplasmic reticulum-Golgi intermediate compartment membrane

Molecular Function

What the gene product does at the molecular level
  • mannose binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.