Gpr173 Gene Summary [Mouse]
Enables gonadotropin-releasing hormone receptor activity. Acts upstream of or within negative regulation of neuron migration. Predicted to be active in plasma membrane. Is expressed in gut; nervous system; and sensory organ. Orthologous to human GPR173 (G protein-coupled receptor 173). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gpr173 |
| Official Name | G-protein coupled receptor 173 [Source:MGI Symbol;Acc:MGI:1918021] |
| Ensembl ID | ENSMUSG00000056679 |
| Bio databases IDs | |
| Aliases | G-protein coupled receptor 173 |
| Synonyms | 3230401K02Rik, G protein-coupled receptor 173, LOC102555688, LOC684078, LOC685576, SREB3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr173 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- gonadotropin-releasing hormone receptor
- protein binding
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the Gpr173 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr173 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to gonadotropin-releasing hormone
- G-protein coupled receptor signaling pathway
- signal transduction
- negative regulation of neuron migration
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity
- gonadotropin-releasing hormone receptor activity