Tsnax Gene Summary [Mouse]
Predicted to enable A2A adenosine receptor binding activity; RNA binding activity; and RNA endonuclease activity. Predicted to contribute to sequence-specific DNA binding activity and single-stranded DNA binding activity. Predicted to be involved in siRNA processing. Located in cytoplasm. Is expressed in several structures, including body cavity or lining; genitourinary system; respiratory system; tail; and vertebral axis musculature. Orthologous to human TSNAX (translin associated factor X). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tsnax |
| Official Name | translin-associated factor X [Source:MGI Symbol;Acc:MGI:1855672] |
| Ensembl ID | ENSMUSG00000056820 |
| Bio databases IDs | |
| Aliases | translin-associated factor X |
| Synonyms | C3PO, DISC1, LOC100039215, translin-associated factor X, TRAX |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tsnax often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Translin family
- NDEL1 binding domain
- Translin and translin-associated factor-X (TRAX)
- binding protein
- self-association domain
- single-stranded DNA binding
- G-protein-coupled receptor binding
- protein binding
- sequence-specific DNA binding
- DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neonatal late-onset sepsis
role in cell
- expression in
- production in
- growth
- migration
- stiffness
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- perinuclear region
- Golgi Apparatus
- Endoplasmic Reticulum
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tsnax gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- posttranscriptional gene silencing by RNA
- spermatogenesis
- cell differentiation
- production of siRNA involved in RNA interference
Cellular Component
Where in the cell the gene product is active
- nucleus
- perinuclear region of cytoplasm
- cytoplasm
- cytosol
- Golgi apparatus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- RNA binding
- metal ion binding
- sequence-specific DNA binding
- single-stranded DNA binding
- A2A adenosine receptor binding
- endoribonuclease activity