Usp24 Gene Summary [Mouse]
Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of protein stability. Predicted to be active in cytosol and nucleus. Is expressed in olfactory cortex. Orthologous to human USP24 (ubiquitin specific peptidase 24). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Usp24 |
| Official Name | ubiquitin specific peptidase 24 [Source:MGI Symbol;Acc:MGI:1919936] |
| Ensembl ID | ENSMUSG00000028514 |
| Bio databases IDs | |
| Aliases | ubiquitin specific peptidase 24 |
| Synonyms | 2700066K03Rik, 2810030C21RIK, B130021E18, KIAA1057, ubiquitin specific peptidase 24 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Usp24 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UBA domain-like superfamily
- Ubl1_cv_Nsp3_N-like
- peptidase
- Ubiquitin carboxyl-terminal hydrolase
- ubiquitin-specific protease
- protein binding
- Peptidase_C19
Pathways
Biological processes and signaling networks where the Usp24 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- gastric cancer
- organismal death
- preeclampsia
- Parkinson disease
- lung cancer
- myocardial infarction
role in cell
- proliferation
- expression in
- quantity
- ubiquitination in
- consumption in
- production in
- cell viability
- dipeptide repeat protein sensitivity
- number
- G1/S phase transition
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Usp24 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein deubiquitination
- proteolysis
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ubiquitin-specific protease activity
- protein binding