Cend1 Gene Summary [Mouse]
Involved in neuron differentiation. Acts upstream of or within adult walking behavior; hindbrain development; and negative regulation of cerebellar granule cell precursor proliferation. Predicted to be located in membrane. Predicted to colocalize with mitochondrion and vesicle. Is expressed in central nervous system; peripheral nervous system ganglion; sensory organ; and urethra. Orthologous to human CEND1 (cell cycle exit and neuronal differentiation 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cend1 |
| Official Name | cell cycle exit and neuronal differentiation 1 [Source:MGI Symbol;Acc:MGI:1929898] |
| Ensembl ID | ENSMUSG00000060240 |
| Bio databases IDs | |
| Aliases | cell cycle exit and neuronal differentiation 1 |
| Synonyms | 1500001H12Rik, AI415214, BM88, C38, cell cycle exit and neuronal differentiation 1, LOC100911402, RGD1309401 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cend1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Cell cycle exit and neuronal differentiation protein 1
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- vesicles
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cend1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- adult walking behavior
- radial glia guided migration of cerebellar granule cell
- cerebellar Purkinje cell differentiation
- negative regulation of cerebellar granule cell precursor proliferation
- cerebellar granular layer maturation
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- membrane
- vesicle
Molecular Function
What the gene product does at the molecular level
- protein binding