Alyref2 Gene Summary [Mouse]
Enables RNA binding activity and single-stranded DNA binding activity. Involved in mRNA transport. Predicted to be located in cytoplasm. Predicted to be part of catalytic step 2 spliceosome; exon-exon junction complex; and transcription export complex. Predicted to be active in nucleus. Predicted to colocalize with chromosome, telomeric region. Is expressed in central nervous system and sensory organ. Orthologous to human ALYREF (Aly/REF export factor). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Alyref2 |
| Official Name | Aly/REF export factor 2 [Source:MGI Symbol;Acc:MGI:1913144] |
| Ensembl ID | ENSMUSG00000060244 |
| Bio databases IDs | |
| Aliases | Aly/REF export factor 2 |
| Synonyms | Aly/REF export factor 2, C130042O11Rik, REF2, Refbp2 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Alyref2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- single-stranded DNA binding
- RNA recognition motif
- protein binding activity, bridging
- RNA binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- catalytic step 2 spliceosome
- Nucleus
- telomeres