Nsa2 Gene Summary [Mouse]
Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to be located in nucleolus. Predicted to be part of preribosome, large subunit precursor. Is expressed in several structures, including branchial arch; extraembryonic ectoderm; neural ectoderm; and trunk mesenchyme. Orthologous to human NSA2 (NSA2 ribosome biogenesis factor). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nsa2 |
| Official Name | NSA2 ribosome biogenesis homolog [Source:MGI Symbol;Acc:MGI:1913883] |
| Ensembl ID | ENSMUSG00000060739 |
| Bio databases IDs | |
| Aliases | NSA2 ribosome biogenesis homolog |
| Synonyms | 5730427N09Rik, CDK105, HCL-G1, HUSSY-29, LNR42, Nsa2p, NSA2 ribosome biogenesis factor, NSA2 ribosome biogenesis homolog, TINP1, YR-29 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nsa2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Eukaryotic/archaeal ribosomal protein S8e and similar proteins
- Ribosomal protein S8e
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nsa2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of 5.8S rRNA
- maturation of LSU-rRNA
Cellular Component
Where in the cell the gene product is active
- nucleolus
- preribosome, large subunit precursor
Molecular Function
What the gene product does at the molecular level
- RNA binding