Trmt61a Gene Summary [Mouse]
Predicted to enable mRNA (adenine-N1-)-methyltransferase activity. Predicted to be involved in mRNA processing and tRNA methylation. Predicted to be part of tRNA (m1A) methyltransferase complex. Predicted to be active in nucleus. Orthologous to human TRMT61A (tRNA methyltransferase 61A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Trmt61a |
| Official Name | tRNA methyltransferase 61A [Source:MGI Symbol;Acc:MGI:2443487] |
| Ensembl ID | ENSMUSG00000060950 |
| Bio databases IDs | |
| Aliases | tRNA methyltransferase 61A |
| Synonyms | 6720458F09Rik, AI606093, C14orf172, FLJ40452, GCD14, Gcd14p, hTRM61, LOC103692719, RGD1359191, TRM61, tRNA methyltransferase 61A |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Trmt61a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
- enzyme
- protein binding
- AdoMet_MTases
- mRNA methyltransferase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Trmt61a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mRNA processing
- tRNA methylation
Cellular Component
Where in the cell the gene product is active
- nucleus
- tRNA (m1A) methyltransferase complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding