B9d2 Gene Summary [Mouse]
Enables gamma-tubulin binding activity. Involved in cilium assembly. Located in membrane. Part of MKS complex. Human ortholog(s) of this gene implicated in Joubert syndrome. Orthologous to human B9D2 (B9 domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | B9d2 |
| Official Name | B9 protein domain 2 [Source:MGI Symbol;Acc:MGI:2387643] |
| Ensembl ID | ENSMUSG00000063439 |
| Bio databases IDs | |
| Aliases | B9 protein domain 2 |
| Synonyms | B9 domain containing 2, B9 protein domain 2, ICIS-1, JBTS34, MGC4093, MKS10, MKSR-2, RGD1566122, stumpy |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse B9d2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- gamma-tubulin binding
- Ciliary basal body-associated, B9 protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ciliary transition zone
- cellular membrane
- basal bodies
- centrosome
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse B9d2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- cilium basal body
- membrane
- cytosol
- TCTN-B9D complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- gamma-tubulin binding