Ppp2r5d

Enables protein phosphatase activator activity. Predicted to be involved in meiotic sister chromatid cohesion; negative regulation of peptidyl-threonine phosphorylation; and protein dephosphorylation. Predicted to act upstream of or within several processes, including positive regulation of neuron projection development; positive regulation of neurotrophin TRK receptor signaling pathway; and regulation of primary metabolic process. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including brain; gonad; hemolymphoid system gland; liver; and lung. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 35. Orthologous to human PPP2R5D (protein phosphatase 2 regulatory subunit B'delta). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppp2r5d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ppp2r5d gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ppp2r5d gene, providing context for its role in the cell.